Aprilaire 4400 air cleaner filters must be replaced twice per year if you have heating and air conditioning or once per year if you have just heating. Aprilaire air 4400 filters are not cleanable or washable. Failure to replace the filters often enough may cause problems with your heating and cooling system. This model has an exclusive remote control which has the ability to turn on your furnace fan just to clean the air in your home or office on a periodic basis.